10 April 2019

Research pick: Vaccination only way to halt childhood disease - "Mathematical model of childhood diseases outbreak with optimal control and cost effectiveness strategy"

Vaccination is the most effective and safe preventive strategy against many childhood infectious diseases. We can vaccinate effectively and safely against potentially lethal and debilitating diseases including measles, mumps, influenza, smallpox, tuberculosis, Rubella, poliomyelitis, and various other diseases. However, there are still outbreaks where vaccination is not available and increasingly in the era of contrarian thinking where vaccines are not taken as an option by some parents for their children, we are seeing the re-emergence of epidemics of these horrendous diseases.

Now, mathematician Kazeem Oare Okosun of Vaal University of Technology, in Gauteng, and Oluwole Daniel Makinde of Stellenbosch University, South Africa, have derived and analysed a deterministic model for the transmission of childhood disease perform optimal control analysis of the model. Writing in the International Journal of Computing Science and Mathematics, they report on how a disease might be controlled optimally to reduce the devastating impact of an epidemic. Their approach also looks at how financial costs might be minimized in efforts to control a childhood disease.

Vaccination has proven to be the most effective prevention strategy against childhood diseases, the team writes, the need to achieve an optimal level of vaccine coverage is essential to controlling the spread of childhood disease in the twenty-first century, they add. Prevention is ultimately better than cure the research suggests especially given that many of the most debilitating and lethal diseases have no effective pharmaceutical, or indeed, any other form of, treatment.

Okosun, K.O. and Makinde, O.D. (2019) ‘Mathematical model of childhood diseases outbreak with optimal control and cost effectiveness strategy’, Int. J. Computing Science and Mathematics, Vol. 10, No. 2, pp.115–128.

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