Botulinum neurotoxins (BoNTs) are a unique group of proteins, with extreme biological activities in areas such as toxins, therapeutics, and cosmetics. The combination of extreme toxicity, nerve as the site of action, and resulting physiologically action of muscular paralysis, has made the botulinum neurotoxin a molecule of elevated anxiety and curiosity. Its use has been attempted as a bioterror agent, a fully developed biological weapon for military use, as a therapeutic agent against numerous neuromuscular disorders and for cosmetic purposes to remove frown lines and facial wrinkles.
The Botulinum Journal - to begin publication in 2008 - provides an international forum and refereed authoritative source of information encompassing varied fields, including microbiology, biochemistry, biophysics, biotechnology, proteomics, genomics, pharmacology, toxicology, drug development related to different forms and types of botulinum neurotoxins, and also Clostridium botulinum.
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