26 September 2012

Special issue: Systems biology approaches in biological and biomedical research

International Journal of Computational Biology and Drug Design 5(3/4) 2012

Papers from the 2nd Workshop on integrative data analysis in systems biology held in Atlanta, Georgia, USA, November 2011, in conjunction with the IEEE BIBM 2011.
  • Network-based approaches for extending the Wnt signalling pathway and identifying context-specific sub-networks
  • Identification of disease-related nsSNPs via the integration of protein sequence features and domain-domain interaction data
  • Functional identification in correlation networks using gene ontology edge annotation
  • Functional classification of genes using semantic distance and fuzzy clustering approach: evaluation with reference sets and overlap analysis 
  • Associating functional groups to multiple clinical types using combined t-test scores and contingency-based measures: a study on breast cancer genes 
  • A linear-time algorithm for finding a maximum-length ORF in a splice graph
  • Integrating image analysis algorithms in a web interface for the quantification of microtubule dynamics
  • Identification of two post-translational modifications via tandem mass spectrometry
  • Peptide sequence tag generation for tandem mass spectra containing post-translational modifications
Additional Paper
  • Fourth generation detour matrix-based topological indices for QSAR/QSPR - Part-1: development and evaluation

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